If you want to remove <br/> tags from product description page .
than Goto
/app/design/frontend/base/default/template/catalog/product/view/description.phtml
copy description file in you’re local theme (template).
app/design/frontend/default/<theme name>/template/catalog/product/view/description.phtml
open local folder description.phtml file and delete “nl2br” tag .
echo $this->helper('catalog/output')->productAttribute($this->getProduct(), nl2br($this->getProduct()->getDescription()), 'description') After Remove nl2br tag . the code is echo $this->helper('catalog/output')->productAttribute($this->getProduct(), $this->getProduct()->getDescription(), 'description')
If you want to remove html tag form other place than use this
strip_tags() // for PHP
$this->stripTags // For Magento